what's new:
  • [Sep 14, 2021] - A new website package of the DiseaseMeth v3.0 were released.
  • [Sep 02, 2021] - The user's manual (help page) was completed.
  • [Aug 28, 2021] - Home page of DiseaseMeth v3.0 was finalized.
  • [Aug 16, 2021] - Disease related DNA methylomes of sequencing based platform were appended.
  • [Aug 08, 2021] - Parameter of methylome samples were transfered to DisMethBrowser while user click the "Gene Symbol" on the querying result pages.
  • [Jul 26, 2021] - The classification information of disease were continuingly used DiseaseMeth v3.0.
  • [Jun 15, 2021] - The DiseaseMeth v3.0 were released with the access link "http://218.8.241.243:8080/DiseaseMeth3.0/".
  • [May 10, 2021] - New tools for cluster analysis, functional survival and correlation analysis were passed the test.
  • [Apr 23, 2021] - All the data in DiseaseMeth were converted into the assembly of UCSC (GRCh37) with LiftOver.
  • [Apr 10, 2021] - A new genome browser called DisMethBrowser was released to provide a more user friendly interface.
  • [Mar 30, 2021] - The Search Engine was redesigned into the fourth query entrance: FunctionSearch.
  • [Mar 21, 2021] - The Search Engine was redesigned into three query entrance: GeneSearch, DiseaseSearch and AdvanceSearch.
  • [Feb 16, 2021] - The collection and pretreatment of Illumina Infinium HumanMethylation850/450/27 BeadChip datasets for 162 disease were completed.
  • [Nov 05, 2020] - The update plans of DiseaseMeth have been drawn up!

Introduction

The Human Disease Methylation Database Version 3.0 is a web-based resource that focuses on the abnormal methylome of human diseases. In the past five years, bulks of large-scale DNA methylation data is available and growing. Our goal is to unearth the changes in disease DNA methylation behind the fragmented data. In particular, we designed a differential analysis pipeline for DMG and calculated 1,485,099 associated genes for 162 diseases. Moreover, DiseaseMeth Version 3.0 provide two tools: Correlation analysis of methylation disease and Cancer prognosis analysis, used to explore the DNA methylation-mediated disease changes and hidden relationship between disease to disease. ...

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Gene Search
Disease Search
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DisMethBrowser

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Analysis

Data

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DiseaseMeth Version

DiseaseMeth
DiseaseMeth Version 3.0
Year
Disease-gene associations
The labels indicate the number of differential methylated genes computed by DiseaseMeth version 3.0.